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Scientific Role of HEK293 in AAV and Lentiviral Production
Luoyang Fudau Biotech Co., Ltd.
Publiziert am 28. November 2025Since its establishment in the 1970s, HEK293 has been a cornerstone platform for viral vector production. In the era of rapid advances in gene therapy and genetic engineering, HEK293 plays an indispensable role in producing AAV (Adeno-Associated Virus) and lentiviral vectors.
1. Why HEK293 is Chosen for Viral Vector Production
The advantages of HEK293 include:
1). High Transfection Efficiency
HEK293 cells efficiently uptake plasmid DNA, enabling high yields of viral particles under transient



